Clinical Efficacy of a New Mouthwash Containing Essential Oil of Cardamom in Reducing Volatile Sulphur Coumpounds Concentration
Suci Erawati, Anton Rahardjo, Sondang Pintauli,
소속 상세정보
( Suci Erawati ) - University of Sumatera Utara Graduate School of Faculty of Dentistry Doctoral Student
( Anton Rahardjo ) - University of Indonesia Faculty of Dentistry Department of Preventive Dentistry
( Sondang Pintauli ) - University of Sumatera Utara Faculty of Dentistry Department of Preventive Dentistry
KMID : 1157520140100040237
Abstract
Objective: The aim of this study was to assess the clinical efficacy of new mouthwash based on kapulaga fruit (Amomum cardamommum L.) containing 0.5% essential oil and compared to 0.5% Listerine? as a positive control and placebo in reducing volatile sulphur compounds (VSCs) concentration of halitosis subjects.
Methods: A randomized, double blinded, cross-over design was conducted among 20 healthy volunteers in Medan, Indonesia. Subjects were divided into 3 groups (Cardamom, Listerine?, placebo group) and instructed to rinse 10 ml of experiment and control mouthwash twice per day for 5 days. After one week washout periods, each group used the opposite mouthwash. The concentration of VSCs, hydrogen sulfide, methyl mercaptan, and dimethyl sulfide were assessed twice daily for 5 days (morning at 5 a.m. and afternoon at 11 a.m.) by using oral chroma and organoleptic measurement. The three mouthwash were analyzed statistically by repeated measures ANOVA.
Results: Either Cardamom or Listerine? was effective in reducing VSCs for up to 4 to 5 hours after mouth rinsing, while placebo not. An analysis showed significant differences of cardamom essential oil in mouthwash and positive control group (p<0.05) from 1st and 5th day while no significant difference in placebo group (p>0.05). Results showed that Cardamom more effective than the other two mouthwashes. Unlike other mouthwash in general, the advantage of cardamom essential oil in mouthwash is alcohol-free, that could avoid from oral pain and sensitivity.
Conclusion: It can be concluded that 0.5% cardamom containing essential oil in mouthwash is useful to overcome halitosis.
키워드
essential oils; volatile oils; halitosis
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